Role of Intraoperative local vancomycin in preventing surgical site infections
Author(s): Dr. Madhuchandra P, Dr. Raju KP and Dr. Shrinidhi IS
Abstract:Background: Surgical site infections following spinal surgeries are a big menace to operating surgeons as well as the patients. It causes increased morbidity and health care costs. Multiple treatment methods and prophylactic measures have been tried to reduce the rates of surgical site infections.
Materials and methods: The study was conducted in our institute from June 2012 to May 2017 for a period of 5 years in a prospective manner. Surgeries were performed by multiple surgeons belonging to different units of the Institute. A total of 200 patients were included in the study and they were categorized into two groups. In first group, intra operative vancomycin was not used (control group) which included 100 patients and second group comprised of another patients in whom prophylactic vancomycin was used intra operatively (antibiotic group).
Results and analysis: Infection rate in the vancomycin group was 3% (3 out of 100 patients). On the contrary infection rate was on higher side in the control group with 8 out of 100 (8%) patients getting infected. There was statistically significant decrease in the rate of infection in vancomycin used group when compared to control group with a ‘p’ value of 0.001.
Conclusion: There was a clear reduction in the rates of surgical site of infections in the antibiotic group. However, further randomized double blind studies with larger patient base and a larger surgical subpopulation is necessary to confirm the efficacy of vancomycin in reducing the rates of surgical site infections.
Dr. Madhuchandra P, Dr. Raju KP, Dr. Shrinidhi IS. Role of Intraoperative local vancomycin in preventing surgical site infections. Int J Surg Sci 2017;1(1):10-13. DOI: https://doi.org/10.33545/surgery.2017.v1.i1a.4
