Abstract: Background and objective: Skin act as a barrier to fluid loss and provide important protection against invasion by micro-organisms. The main objective of the present study is investigated the effect of different bacteria’s presenting in ulcers on take-up of skin grafting.
Research design: The observational and clinical design was applied in the purpose of the present study.
Method: total 100 patients who admitted in the department of surgery and plastic surgery ward were included in present study.
Result: The graft lass was significant in ulcers colonized with Staphylococcus aureus bacteria when compared with ulcers with no growth (p=0.037). In our study the graft loss was significant in Pseudomonas infected ulcers when compared to ulcers with no growth (p=0.40). Ulcers when colonized with Klebsiella, Proteus, E. coli, Citrobacter graft take above 90%, it was observed in 20/34(58.8%) of the patients, while in ulcers with no growth 17/23(73.9%), (p=0.40) it is positively significant.
Conclusion: findings of the study we are concluded that the colonization of ulcers by Pseudomonas aeruginosa and Staphylococcus aureus relatively poor graft survival, and the other bacteria like Klebsiella, Proteus, E. coli, Acinetobacter etc, had a higher graft survival compared to other bacteria.