Vol. 3, Issue 1, Part C (2019)

Abstract: A randomized control study was conducted at Heritage Institute of Medical Sciences (HIMS) Varanasi to evaluate clinical efficacy of cefuroxime compared with amoxicillin+clavulanate for prevention of wound infection in patients undergoing open prolene - mesh hernioplasty in cases of inguinal hernia. There was minimal difference in overall wound infection rates between cefuroxime and amoxicillin+clavulanate group and side–effects in cefuroxime group were slightly less. Therefore, cefuroxime appears to be slightly more effective antibiotic for use as surgical prophylaxis.