Objective of this study is to test the efficacy of topical hemocoagulase in bleeding control, wound reduction, epithelialization in non-healing and healing ulcers/wounds after debridement in comparison with conventional method of treatment.
Materials and Method: A prospective comparative study was conducted in JSS Hospital, Mysuru, Karnataka from August 2016 to October 2018. The source of data was patients attending the outpatient on a regular basis or those admitted as inpatients for the management of healing and non-healing ulcers. 60 patients were studied. 30 cases were randomly chosen for study with topical hemocoagulase and 30 cases received conventional dressing for healing/ non healing ulcers.
Results: Topical Hemocoagulase showed faster and better healing rates. The mean area reduction was statistically significant in the study group. The median baseline surface area of the wound at the beginning of the study was 40.00 among cases and 13.5 among the controls and there was no statistical difference between the cases and the control before initiation of the treatment. Post interventions the median surface area of the ulcer in cases were 13.5 and 16.0 among control. Decrease in surface area of the wound median value in cases were 20.50 and & among controls, which shows statistical significance. There were no adverse effects or reactions seen with the use of Topical Hemocoagulase among the study group.
Conclusion: This evaluation provides strong evidence that Topical Hemocoagulase dressings provide safe and cost effective method of enhancing the healing rates of non-healing wounds, reducing the overall hospital stay and morbidity.