Abstract: Back Ground: Helicobacter pylori
are the most common chronic bacterial infection, and a significant etiological factor in acid peptic diseases and gastric cancer. Dyspepsia is a common gastrointestinal disorder, and the most common indication for gastroscopy. Detection of H. pylori
during endoscopy has become standard clinical practice.
Objective: To detect the different underling OGD causes of dyspeptic symptoms in patients presented to the outpatients clinic of the gastroenterology unit in Al-Ramadi General Hospital, and to evaluate the role of H. pylori in relation to the different OGD results.
Methods: One hundred patients with various upper gastrointestinal complaints were investigated for evidence of H. pylori infection and its possible relation to the upper gastrointestinal disease. Multiple biopsies from the antrum of the stomach were taken through fiber optic endoscope from these patients. Diagnosis of H. pylori infection was done by the urease test.
Results: One hundred patients, (62 males, 38 females), with age range between (9-63) year old and a mean age of 36 year old, were included in this study. Urease test was positive in (48%) of all patients (46% in male, 50% in female). Urease test was positive in 82% of patients with duodenal ulcer, 75% with Gastric carcinoma, 60% with gastric ulcer, 50% with gastritis, 50% with duodenitis, 41% with esophagitis, 37% with normal looking mucosa.
Conclusion: H. pylori were more likely associated with DU than GU. There is a high association between H. pylori and CA stomach. H. pylori was found in about 1/3 of patients with normal OGD and its difficult to tell about its role in this group of people. Most patients with positive OGD and negative urease test were found to have other predisposing factors such as NSAID or cigarette smoking. CA stomach was the least likely cause of upper GI symptoms. About half of the patients with upper GI symptoms have normal OGD which could either indicates functional dyspepsia or other causes of dyspepsia like liver, gall bladder or pancreatic diseases.