Background: After surgery, an infection that occurs in the part of the body is called surgical site infections.
Aim: The present study aimed to evaluate the role of antibiotic administration prophylactically to achieve clean contaminated surgical cases and to study if antibiotic administration is sufficient to reduce the surgical site infection.
Materials and Methods: This is a prospective study which consisted of 90 cases admitted to SVS Medical College, Mahabubnagar from January 2017 to December 2019 for a period of 2 years. 90 cases were selected in this study and they were divided into two groups which were group I who received 1gm ceftriaxone intravenously half an hour before surgery and Group II who didn’t receive any antibiotic before surgery.
Results: Group I had 35 clean surgical cases and 10 clean contaminated cases, and none of them were infected. In group II, 1 case was infected and out of 10 clean contaminated cases, 4 cases were infected. Third generation cephalosporins was administered in group I patients under aseptic conditions half an hour before the surgery, in group I, no patient was infected. In group II, infection rate of 2.86% (1 patient) in clean cases and 40% (4 patients) in clean contaminated cases. No side effects like allergy were reported after administering prolonged prophylactic drug. The P value was 0.3117 and it was significant.
Conclusion: This study concluded that there is no need for prophylactic antibiotics in clean surgeries, as no statistically significance was observed, and statistical significance was observed in clean contaminated cases.