Vol. 7, Issue 1, Part A (2023)

Hepatocellular carcinoma is one of the most common malignancies which is the third leading cause of cancer-related deaths worldwide. HCC is commonly caused chronic hepatitis. We report a 78 year old male patient from Tumkur city presented with chief complaints of weight loss since 6 months who was a was a known case of hypothyroidism, Type 2 Diabetes Mellitus and Hypertension. USG abdomen and pelvis showed cirrhosis of liver and well defined soft tissue lesion measuring 60*55 mm with internal vascularity noted in segment 5 of liver and CECT abdomen showed changes of chronic liver disease and well defined hypodense lesion in segment 5 of liver. PET CT report showed mildly hypermetabolic lesions in the liver and scan features were concerning for multicentric HCC. Histopathological examination showed tumor comprised of malignant hepatocytes arranged in glandular, acinar and trabecular pattern.