Abstract: Introduction: Breast cancer is the most common cancer in women worldwide. Breast diseases include a variety of lesions including inflammatory, neoplastic and hormonal response disorders. Sometimes it is difficult to determine whether a suspicious lump in the breast is benign or malignant, simply with clinical examination and FNAC. Both FNAC and Trucut biopsy are complementary procedures. So the present study was conducted to determine the efficacy of FNAC vs Trucut biopsy in diagnosis of breast lump. Aims and Objectives: 1. To compare the diagnostic accuracy of FNAC and Trucut biopsy in differentiating benign and malignant lesions of palpable lump in breast. 2. To analyze sensitivity, specificity, PPV and NPV and the efficacy of FNAC and Trucut biopsy. 3. How an OP procedure of FNAC can be effective in arriving at diagnosis in carcinoma breast as treatment. 4. To analyse cost-effectiveness of FNAC and Trucut biopsy.
Materials and Methods: This was a single centre, prospective, comparative study conducted from October 2022 to September 2023. It was carried out on 40 patients who were satisfying inclusion criteria.
Results: Sensitivity of FNAC was 76.92% with a specificity of 96.2% and a PPV and NPV of 90.9% and 89.65% respectively. Accuracy rate for diagnosing malignant lesions by FNAC was 90%. Sensitivity and specificity of Trucut biopsy was 85.7% and 100% with a PPV of 100% and NPV of 92.85%. Accuracy rate for diagnosing malignant lesions by Trucut biopsy is 100%.
Conclusion: It can be concluded that FNAC can be done with minimal pain and immediate report but, Trucut biopsy is superior to FNAC in diagnosis of breast lump as it can get Histopathology report, it can be performed as an outpatient surgery and can avoid unnecessary surgery in case of benign disease and early intervention in case of malignancy.
