Manuscript Writing Service
International Journal of Surgery Science
Printed Journal   |   Indexed Journal   |   Refereed Journal   |   Peer Reviewed Journal

Vol. 8, Issue 4, Part B (2024)

Visual outcomes and foveal avascular zone changes in diabetic macular edema patient’s Post-ranibizumab treatment

Author(s): Ehabeldin Mohamed Magahwry
Abstract:
Background: The permanent and disability-inducing vision loss is mostly caused by diabetic retinopathy (DR) and clinically severe macular edema. This study set intended to evaluate the effects of ranibizumab on diabetic macular edema (DME) patients' visual outcomes and any changes to their foveal avascular zone (FAZ). 
Methods: This single-arm interventional study enrolled 30 eyes of 30 diabetic patients, aged ?18 years, both sexes, and had DME requiring an intravitreal injection of ranibizumab (macular thickness >400 micron) as confirmed by optical coherence tomography angiography and fluorescein angiography. Three doses of Ranibizumab were administered intravitreally to each patient, with a one-month interval between each dosage.
Results: Best corrected visual acuity was significantly lower at (1, 2 and 3 months) than pretreatment (P<0.001). The contrast sensitivity test and normal color vision test were significantly higher at (1, 2 and 3 months) than pretreatment (P<0.05). Intraocular pressure (IOP) was insignificantly different between (1, 2 and 3 months) and pretreatment. FAZ area in superficial capillary plexus and FAZ area in deep capillary plexus was insignificantly different between (1, 2 and 3 months) and pretreatment. Fundus examination significantly improved at 3 months than 1 month (P=0.009) and was insignificantly different between 1 and 2 months.
Conclusions: Analyzing the form and size of FAZ is likely crucial for identifying pathological macular changes and forecasting visual outcomes in DR.
Pages: 82-86  |  28 Views  14 Downloads


International Journal of Surgery Science
How to cite this article:
Ehabeldin Mohamed Magahwry. Visual outcomes and foveal avascular zone changes in diabetic macular edema patient’s Post-ranibizumab treatment. Int J Surg Sci 2024;8(4):82-86. DOI: https://doi.org/10.33545/surgery.2024.v8.i4b.1122
 
International Journal of Surgery Science
Call for book chapter